[Sincerely appeal to friends with little babies, do not use nimesulide granules for antipyretic treatment of children’s fever. The trade name is Ruizhiqing. Since work, I have met five such patients, with Wright’s syndrome and four invalid rescue deaths! Another little angel left tonight, hoping to tell friends with babies that this medicine has been banned for children under 12 years old, and they should not go to private pharmacies and clinics to listen to poor doctors and give it to children. From ICU doctors of children’s hospital]
In the past two days, some netizens have seen the above information in WeChat, and some netizens have asked me to verify the authenticity of this information. I will analyze it here. On closer examination, the content of this information is true or false.
Truth 1: [Nimesulide Prohibits Children Under 12] Is True
Nimesulide is a non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic effects.
Nimesulide was listed in China in 1997. Initially, the indications approved in the drug instructions were [treatment of symptoms such as chronic arthritis, pain and inflammation after surgery and acute trauma, fever caused by upper respiratory tract infection, etc.].
In 2011, the former State Food and Drug Administration adjusted the instructions for clinical use of nimesulide based on the adverse reaction monitoring report of [nimesulide], research and supervision at home and abroad, and expert opinions. The indications were revised to [prohibited for children under 12 years old; As a second-line anti-inflammatory and analgesic drug, it can only be used when at least one other non-steroidal anti-inflammatory drug fails to treat. Indications are limited to pain of chronic arthritis (such as osteoarthritis, etc.), pain after surgery and acute trauma, and symptom treatment of primary dysmenorrhea].
Truth 2: [Don’t go to private pharmacies and clinics to listen to those lame doctors] is right.
Nimesulide is a prescription drug and is forbidden for children under 12 years old. It must be used under the guidance of professional doctors in regular hospitals.
Private pharmacies and some poor doctors in non-standard clinics may not update their medication knowledge in time.
Truth 3: [Nimesulide-induced Reyes Syndrome, five of which have been encountered since work] is false
We know that children using aspirin may develop Wright’s syndrome, which is a serious brain disease, but we have never seen or heard of cases of Nimesulide causing Wright’s syndrome. It is even more incredible that a doctor meets five cases.
In fact, this drug is forbidden to children, mainly because of hepatotoxicity, not Reyes syndrome!
Since 1999, Liver damage caused by nimesulide is of concern, The European Drug Administration conducted three risk/benefit evaluations of the drug in 2002, 2007 and 2008 respectively. The final evaluation opinions are as follows: The clinical benefits of nimesulide outweigh the risks, However, considering the risk of liver damage caused by the drug, The European Drug Administration has taken a series of risk control measures, Including stipulating that the drug can only be used as a second-line drug for the treatment of acute pain, painful osteoarthritis, primary dysmenorrhea and other symptoms, banning children under 12 years old, limiting the maximum daily dose and course of treatment, increasing contraindications, etc. This is consistent with the regulatory measures taken by China in 2011 to revise the instructions.
Truth 4: [Transferred from ICU Doctor of Children’s Hospital] Is False
Netizens @ My verification version has many endings, some of which are [transferred from ICU doctors in Children’s Hospital], some of which are [transferred from ICU doctors in Concorde Hospital], and some of which are [transferred from ICU doctors in Nanjing Children’s Hospital].
These endings have a common feature: ICU doctors have no first name or surname, and there is no such person!
To add a seemingly authoritative ending to such information, the writer must have deliberately stimulated parents’ desire to spread, so this information will not be written by ICU doctors.
Hint: The medicine is divided into three parts, Drugs will inevitably have adverse reactions, The key to selection is to weigh the pros and cons. Parents of antipyretic drugs for children should try their best to choose relatively safe drugs. The World Health Organization recommends that the two classic antipyretic drugs for children widely used in the world are [acetaminophen] and [ibuprofen], which must be used according to the recommended dosage in the instructions, not exceeding the dosage, and not for a long time.