Precautions for Several Major Drugs in Myasthenia Gravis Patients
Statins and Myasthenia Gravis 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor) have that effect of reducing blood lipid and anti-inflammation, It can reduce the incidence of cerebrovascular diseases and coronary heart disease. In the past 10 years, the application of statins has increased significantly. Although most patients are generally well tolerated to statins, the drugs still have certain side effects, such as myalgia and rhabdomyolysis in severe cases. In theory, Statins may induce or aggravate myasthenia gravis symptoms, However, it is not caused by affecting the transmission of neuromuscular junctions. Pharmacological mechanism studies have found that, Statins can inhibit T cell activation, Inducing the transformation of helper T (Th) cells to Th2 cells, acting on B cells Read More …