Diuretics, a classic antihypertensive drug, are suitable for patients with more salt intake, elderly hypertension, simple systolic hypertension, accompanied by heart failure and lower limb edema, and are also one of the basic drugs for refractory hypertension. Commonly used drugs: Diuretics commonly used to control blood pressure are mainly thiazide diuretics, such as hydrochlorothiazide and indapamide. The drug effect is similar to hydrochlorothiazide. Small doses of thiazide diuretics (such as hydrochlorothiazide 6.25 ~ 25mg) have little effect on metabolism, and can significantly increase the antihypertensive effect when combined with other antihypertensive drugs (especially ACEI or ARB, such as enalapril, valsartan, etc.). Adverse reactions: The adverse reactions of these diuretics are hypokalemia and hyperuricemia. Weak fatigue, abdominal distension and palpitation occur. Read More …