Precautions for surgery and anesthesia in myasthenia gravis patients

Precautions for surgery in patients with myasthenia gravis As it is a rare disease, Many hospitals have to ask neurology consultation to determine the surgical indications and anesthesia methods after surgical treatment of myasthenia gravis patients with patients requiring surgery. In fact, the basic principle of clinical medicine is to [solve the main contradiction at present], If the patient’s surgery is imminent, Such as intestinal obstruction or spleen rupture, No matter what happened to the previous myasthenia gravis, emergency surgery is required. Even if the operation will aggravate myasthenia gravis, there is no need to worry about it. Because if the current surgical situation is not handled in time, it will endanger life. Therefore, emergency surgery for myasthenia gravis patients Read More …

Problems related to ocular muscles in myasthenia gravis patients

Why is the levator palpebrae muscle of myasthenia gravis patients most vulnerable? The first common symptom of myasthenia gravis patients is ptosis, But its mechanism is not clear. Some scholars believe that the levator palpebrae superior muscle is different from other extraocular muscles. For fast shrinkage fibers, It has a high anti-fatigue property and is a muscle fiber that is not innervated by multiple nerves. The levator palpebrae superior muscle has been stimulated by nerve impulses when opening eyes, so its compensation space is small under pathological conditions, and the [reserve] to deal with pathological changes is insufficient, resulting in the safety factor of neuromuscular transmission being easily affected and more easily fatigued than other muscles. Some studies have also Read More …

Precautions for Several Major Drugs in Myasthenia Gravis Patients

Statins and Myasthenia Gravis 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor) have that effect of reducing blood lipid and anti-inflammation, It can reduce the incidence of cerebrovascular diseases and coronary heart disease. In the past 10 years, the application of statins has increased significantly. Although most patients are generally well tolerated to statins, the drugs still have certain side effects, such as myalgia and rhabdomyolysis in severe cases. In theory, Statins may induce or aggravate myasthenia gravis symptoms, However, it is not caused by affecting the transmission of neuromuscular junctions. Pharmacological mechanism studies have found that, Statins can inhibit T cell activation, Inducing the transformation of helper T (Th) cells to Th2 cells, acting on B cells Read More …

Is myasthenia gravis related to thymus what?

Thymus is located in the anterior mediastinum of the thoracic cavity behind the sternum. It is an important lymphoid organ of the human body. Its function is closely related to immunity. During the late embryo and birth, the human thymus weighs about 10-15g. With the growth of age, the thymus continues to develop and reaches puberty about 30-40g. After that, the thymus gradually degenerates, lymphocytes decrease, adipose tissue increases, and only 15g is reached in the elderly. According to incomplete clinical statistics, 90% of myasthenia gravis patients have thymus abnormalities, about 70% have thymus hyperplasia and 10-15% have thymoma. Some patients have obvious improvement of symptoms and obvious decrease of AChR antibody titer after thymectomy, which all indicate that thymus Read More …

How to Improve the Quality of Life of Myasthenia Gravis Patients

What should be paid attention to in the diet of myasthenia gravis patients? Western medicine does not have too many restrictions on the diet of myasthenia gravis, while traditional Chinese medicine suggests eating less cold food, such as mustard, radish, mung bean, kelp, laver, watercress, day lily, sword flower, watermelon, balsam pear, etc. Eat more foods rich in high protein, such as chicken, duck, fish, lean meat, tofu, soybeans, eggs, vegetable protein and animal protein, as well as fresh vegetables and fruits, and pay attention to the digestibility of food. Should Myasthenia Gravis Patients Pay Attention to what in Their Life? This disease is a chronic disease with a long course of disease. Patients need to pay attention to the Read More …

What about myasthenia gravis patients complicated with hyperthyroidism?

Hyperthyroidism and myasthenia gravis may occur successively or simultaneously, Myasthenia gravis can occur at various stages of hyperthyroidism. Both diseases are essentially autoimmune diseases. Just like the two enterprises funded by the same consortium, the source is the same, and there may be a common pathogenesis basis between the two: the cross-immune response of the common immune target organ-eye muscle and the common genetic background. All newly diagnosed myasthenia gravis patients should be screened for hyperthyroidism. If the two diseases occur at the same time, both should be considered in treatment. Generally speaking, there is no conflict in the treatment of the two diseases. If there is no medical contraindication, glucocorticoid therapy can be applied, thymectomy (for myasthenia gravis) can Read More …