Is the risk of osteoporosis increased in myasthenia gravis patients compared with normal people? Let’s take a look at the hints of the recent study of two large samples. There was no statistical difference in the probability of fractures or osteoporosis-related fractures in patients with myasthenia gravis A British study published in 2013 conducted a retrospective cohort study of 1066 myasthenia gravis patients from 1987 to 2009, with age and sex-based controls. The results showed that the probability of fracture or osteoporosis-related fracture in myasthenia gravis patients showed no statistical difference compared with the control group, and their adjusted risk ratios (AHR) were 1.11 and 0.98 respectively. In addition, among myasthenia gravis patients, those who used oral glucocorticoid more than Read More …

First solve the ventilation problem Although myasthenia gravis crisis includes cholinergic crisis, myasthenia crisis and antagonistic crisis, it is often difficult to accurately identify them in clinical work. In any case, rapid improvement of patient ventilation is the primary task to solve the crisis. Early patients show more prominent carbon dioxide retention than hypoxemia. Therefore, we should not rely on the oxygen saturation monitoring value on the monitor, but should closely follow up the arterial blood gas. If there is typical type II respiratory failure, we should give mask balloon assisted ventilation in case of emergency, followed by tracheal intubation/tracheotomy and artificial respiration assisted respiration immediately. Attention should be paid to frequent lung auscultation and examination of cannula position. In Read More …