Screening for ABO blood group incompatibility between mother and child is not routinely recommended during prenatal examination. The reasons are as follows: 1. There is no direct relationship between the antibody level in mother’s blood and ABO hemolysis of newborn, Therefore, even if anti-A and anti-B antibodies are found in the blood of pregnant women, Nor does it advocate reporting the results. 2. Even if the possibility of fetal hemolysis is suspected during pregnancy, There is no evidence-based medical evidence to prove that drug therapy is effective. 3. ABO hemolysis has few serious consequences. Because after the anti-A and anti-B antibodies enter the fetus, It will combine with various fetal cells, The number of antibodies that actually bind to fetal red blood cells is relatively small. In addition, The A and B antigens on the surface of fetal erythrocytes are not fully developed and mature, The diagnosis of ABO hemolysis mainly depends on the onset of jaundice on the first day of birth, Serious hemolysis requires blood transfusion treatment is very rare. Since there is no direct relationship between the antibody level in the mother’s blood and ABO hemolysis of the newborn, there are no drugs that can be used for effective treatment, and there are no serious consequences of what, why should screening be carried out? Why should people and money be wasted to increase the anxiety of expectant mothers? Forget it, stop it and connect with the international community.
