Gout is closely related to kidney. Most friends with hyperuricemia and gout have the problem of reduced uric acid excretion by kidney. In turn, persistent high uric acid levels in the body will also cause further damage to the kidneys.
10% ~ 25% of gout friends will have uric acid stones in their kidneys. If the stone is small, it may be discharged out of the body with urine without obvious symptoms. For larger stones, waist pain, renal colic, hematuria, etc. may occur, and renal failure caused by hydronephrosis may also occur for long-term serious renal stones.
Therefore, for gout friends, it is very necessary to master scientific kidney protection methods to avoid serious kidney damage.
Drink plenty of water and urinate frequently.
For friends with normal heart function and kidney function, it is recommended to drink more than 2 liters of water per day.
Kidney to uric acid excretion has a very important function, under normal circumstances, most of the uric acid in the body is excreted through the kidney with urine. When it comes to benzbromarone, I believe everyone will not be unfamiliar with it. It is through increasing the kidney’s ability to excrete uric acid, thus playing a role in reducing blood uric acid and treating gout.
The kidney can excrete uric acid in the body through urine, but if drinking water is insufficient, the uric acid accumulated in the kidney and ureter naturally cannot be excreted with urine. Over time, a large amount of urate will form kidney stones and urinary tract stones, thus causing renal colic, hydronephrosis and other conditions.
The way to deal with this is to drink more water and produce enough urine. Especially friends who are taking benzbromarone should pay more attention to this problem.
It is very important to reach the standard if uric acid is to be lowered.
It is suggested that the blood uric acid should be controlled below 360 mol/L; For friends with tophus, the blood uric acid should be reduced to below 300 mol/L.
Gout and hyperuricemia are chronic diseases. The key to long-term successful control of gout lies in insisting on improving living and eating habits, taking necessary uric acid-lowering drugs, and regularly detecting the level of uric acid in blood to ensure that its concentration is maintained within the target range.
Lower levels of uric acid usually accelerate the dissolution of tophus and minimize the recurrence rate of gout. However, high levels of uric acid not only easily form stones, but also directly damage renal tubules and interstitium.
Standardized medication, drugs can not hurt the kidney
Some friends may say [since the medicine is three points poisonous, why take the medicine to reduce uric acid]?
In short, this is the result of weighing the pros and cons. If you don’t take medicine, uric acid will remain high for a long time. Not only will gout attack more frequently, but also adverse events such as gout stone, renal failure, myocardial infarction and stroke will occur.
Some uric acid-lowering drugs may indeed cause skin damage, gastrointestinal discomfort, liver and kidney damage and other [side effects], but as long as they cooperate with the doctor’s examination, regularly review and use drugs under the guidance of the doctor, the doctor will be told immediately if there is any abnormality, and these [side effects] can also be controlled.
Be careful of Chinese herbal medicine
No matter traditional Chinese medicine or western medicine, misuse may cause damage to the kidney. Don’t believe in [kidney-protecting] drugs under the slogan of [natural no side effects], no side effects are often deceptive.
Kidney is like the body’s garbage cleaning field. Most drugs are excreted through the kidney after being treated by the liver. Chinese herbal medicines such as aristolochia, Aristolochia manshuriensis and some Chinese herbal decoctions with unknown components have definite toxic and side effects on the kidney, which will directly cause acute kidney damage or chronic kidney function damage caused by long-term administration.
Therefore, gout friends must not blindly use the so-called Chinese herbal medicine with [kidney-protecting effect].
Regular review to understand their renal function
Regular review of liver and kidney function, kidney B-ultrasound or CT and other examinations according to specific conditions can understand kidney function and avoid further damage.
As mentioned earlier, many friends with high uric acid and gout will have kidney stones, and kidney B-ultrasound can find stones in the kidney, thus making treatment adjustments according to the situation to avoid further kidney damage. For example, benzbromarone is usually not used for gout patients with kidney stones.
However, creatinine and urea nitrogen can understand the actual function of the kidney and adjust the treatment plan in time. For example, for patients with obvious abnormalities in renal function, febustat is the first choice for controlling uric acid. If allopurinol is selected, the dosage of drugs must be adjusted according to renal function.