Some studious people may think of the 114 carcinogens defined by the International Agency for Cancer Research (IARC) under the WHO, but for a specific type of cancer, it is difficult to trace the cause. For example, pancreatic cancer is hard to say whether it is caused by what? From a macro perspective, genetic factors account for only 5% and environmental factors account for 95%. [2] Among them, diet and obesity (30%-35%) account for the largest proportion. In addition, smoking accounts for 25-30%, inflammation accounts for 15-20%, sexual factors account for about 7%, alcohol and radiation, etc. Can diet and obesity really cause cancer? When you think of cancer patients, most people think of skinny patients lying in hospital beds. But statistics say that fat people are more likely to suffer from cancer? ! Is it unscientific? Obesity can cause many diseases, Including coronary heart disease, stroke, hypertension, diabetes and osteoarthritis, These common sense has gradually been accepted by the Chinese, However, the cause of cancer is still unknown. The National Cancer Institute agrees that more than a third of newly diagnosed cancer patients in 2013, It is caused by overweight and obesity caused by diet quality and quantity problems and lack of exercise (activity). [3] Based on the conclusion drawn from 28 large studies [4], At present, it has been confirmed that the incidence of cancers that can be increased due to obesity include esophageal cancer, pancreatic cancer, intestinal cancer, breast cancer (postmenopausal), endometrial cancer, kidney cancer, thyroid cancer and gallbladder cancer. Why does obesity cause cancer? To sum up, there are five mechanisms: 1. Excessive adipose tissue produces excessive estrogen, Increases the risk of breast cancer and endometrial cancer. 2. Blood insulin and insulin-like growth factor-1 (IGF-1) levels in obese people are often relatively high. IGF-1 can promote the progression of some tumors. 3. Some hormones produced by adipocytes, For example, leptin, Can promote cell proliferation, Adiponectin, Adipocytes can directly and indirectly act on mammalian rapamycin target protein (mTOR) and AMP-activated protein kinase (AMP-activated protein kinase). The former regulates cell growth, motility, cell survival, There is also protein synthesis. The latter is an enzyme involved in cell energy balance. 5. Obese people are often accompanied by chronic [subacute] inflammation, which is associated with an increased risk of cancer. What are obese? Belgian mathematician Lambert Adolphe Jacques Quetelet put forward the Body Mass Index (BMI) in the middle of the 19th century, which translates into body mass index or height body mass index, weight (kg)/height (m) square. According to this standard, BMI is light < 18.50 severe < 16.00 moderate 16.00-16.99 mild 17.00-18.49 normal range 18.50-24.99 overweight ≥ 25.00 pre-obesity 25.00-29.99 obesity ≥ 30.00 first-degree obesity 30.00-34.99 second-degree obesity 35.00-39.99 third-degree obesity ≥ 40.00 BMI < 18.5, light weight; 18.5-24.99, normal range; > 25-29.99, overweight; ≥ 30 or above is obesity. For an adult who is not overweight, white adipose tissue accounts for 20% of men’s weight and 25% of women’s weight. Obese people are the increase of white adipose tissue. What are the reasons for obesity? Apart from a very small number of hereditary and medical causes and mental illness, The main causes of obesity are excessive calorie intake and reduced exercise. Various data point out that Except for some poor and backward areas, The average amount of food available per person per day has been increasing all over the world. In the United States and Europe, Some agricultural policies and technologies have led to a relative reduction in food prices, All kinds of food programs are flooding all kinds of media, Heart rate, respiration, blood pressure and body temperature are vital indications. BMI is the most healthy indicator. More than 25 is unhealthy, Obesity is disease. Anyway, No one is pulling your ear to feed you, No one will pry open your mouth and give you all kinds of sugary drinks. Only you can take care of your mouth. Cancer can be prevented by quitting smoking, drinking, getting vaccinated, and having a single fixed sexual partner. But the most important thing is to control the quality and quantity of the diet. Increase exercise, Don’t be overweight. If human beings and cancer are compared to a protracted war, then weight loss has become the first key to fighting cancer. WHO believes that at least one third of cancers can be prevented. Prevention is the best policy, early diagnosis is the best policy, and treatment is the worst policy. Don’t be overweight should be promoted as a national health education plan to reduce medical pressure and social costs. Do you want to keep slim, fully demonstrate self-confidence and prevent and block cancer?
