HPV vaccine finally went on sale at the end of July 2017!
Its function is to prevent HPV infection, and high-risk HPV is the most important factor leading to cervical cancer. Therefore, HPV vaccine is also called cervical cancer vaccine.
Its listing is undoubtedly a good news for the health of the majority of women. Many women want to know more: can they fight? Don’t you have to worry about cervical cancer after playing? How old is it for a girl to take this vaccine?
Dr. Clove asked Tian Jishun, an obstetrician and gynecologist, and Dr. Taulina of the Center for Disease Control and Prevention to give a detailed answer to the common problems of cervical cancer vaccine.
Can 28-year-old women who have sex be vaccinated against cervical cancer?
Tian Jishun (Obstetrician and Gynecologist of Clove Clinic) A:
Injections may still be useful, but from the perspective of cost performance, I do not recommend them for the following reasons:
1. The recommended age for vaccination is 9-12 years old, and replanting can be carried out for 13-26 years old. The best vaccination is before the first sexual life. Although there are guidelines that 3 doses of HPV vaccine for women aged 27-45 years old also have certain preventive effects, the benefits will be reduced.
2. If you have sex, you may have been infected with HPV. If you have been infected, the effect of vaccination is obviously much smaller.
3. Judging from the cost-benefit ratio, vaccination at a young age will take longer to benefit. The older you get, the less money you spend, the shorter the benefit time, which is not cost-effective.
4. Cervical cancer can be screened. According to the screening strategy of cervical cancer, there is a great chance to find the problem before it develops to cervical cancer, and then solve it as soon as possible, which can also prevent the development to cervical cancer.
Which should I choose between [bivalent] and [bivalent] vaccines?
Tao Lina (Shanghai Center for Disease Control and Prevention) Answer:
GlaxoSmithKline’s bivalent vaccine is on the market this time, which only prevents types 16 and 18 viruses, but for cervical cancer, these two types of viruses are the most harmful.
Mercadon’s 4-valent and 9-valent vaccines can also prevent the type 2 virus.
Judging from the current research, Mercadon’s vaccine antibody effect is slightly inferior to GlaxoSmithKline’s bivalent vaccine, but there is no evidence as to whether the actual prevention effect is also slightly inferior.
Since 4-valent and 9-valent vaccines also prevent other types, I personally prefer to use 9-valent vaccines. However, Mercadon vaccine is not listed on the mainland, and the specific date of listing cannot be determined.
If it is more convenient to go to Hong Kong, it is suggested that you can get a 9-valent vaccine. If it is not very convenient, then wait for the first half of next year after the market, vaccinate bivalent vaccine.
There is no need to detect HPV infection before inoculation.
Is Hong Kong’s vaccine better? Can’t you get cervical cancer after being vaccinated?
Tian Jishun (Obstetrician and Gynecologist of Clove Clinic) A:
Judging from the news, bivalent vaccines are listed in China, while HPV vaccines in Hong Kong or abroad have 4-valent or 9-valent vaccines, which means more HPV types are targeted.
In terms of coverage, Hong Kong and foreign countries are indeed better. Apart from cervical cancer, they can also prevent vaginal cancer, anal cancer and genital warts. However, cervical cancer is only targeted in China.
However, the effectiveness of preventing cervical cancer in China and Hong Kong is the same.
It is not to say that cervical cancer can be prevented by vaccination. The two subtypes targeted by domestic vaccines have led to 70% of cervical cancer. Vaccines can reduce the incidence of this part of cervical cancer. However, HPV, which causes cervical cancer, has other subtypes and is not within the scope of prevention (4-valent and 9-valent cannot be completely covered).
Therefore, even if HPV vaccine is vaccinated, cervical cancer screening should be carried out according to the regular cervical cancer screening strategy.
Is it true that men can also be vaccinated against HPV?
Tian Jishun (Obstetrician and Gynecologist of Clove Clinic) A:
The bivalent vaccine approved for listing in China is only suitable for types 16 and 18, so it is only suitable for women.
However, the 4-valent and 9-valent HPV vaccines listed in Hong Kong and abroad can indeed be vaccinated by men, which can prevent anal cancer, penis cancer and genital warts.
However, due to the low incidence rate of male-related malignant diseases, due to the consideration of cost-benefit ratio, some people also think that the cost-performance ratio is not high and the necessity is not great.
If men are vaccinated with HPV vaccine, it is recommended to vaccinate with 9-valent instead of 4-valent because the coverage is larger.
Age recommended 9 ~ 12 years old, have not been vaccinated before, 13 ~ 21 years old can also be replanted. The best time to vaccinate is before the first sex life, if you have sex life, you can also play within the vaccination age, but the benefits will be reduced. 22 ~ 26 years old vaccination, foreign insurance does not cover.
Important reminder: besides vaccines, regular screening is also very important. One-fourth of cervical cancer patients in our country have never been screened before detection, resulting in missing the opportunity of early detection and treatment.